BreastCancers: My dad and his sister had breast cancer, what is MY risk for the disease

My dad and his sister had breast cancer, what is MY risk for the disease?
Dad and Aunt both had breast cancer. Dad had radical mastectomy as did Aunt. Aunt recovered and is 80 years old. Dad died of a different cancer in his late 60's. Their sister, another aunt, died of Leukemia in her 20's and Granddad died of liver cancer in his 70's. What risk do my siblings and I have of developing cancer? Are my brothers also at a higher risk of breast cancer?
Cancer - 8 Answers
Random Answers, Critics, Comments, Opinions :
1 :
Everyone's at a higher risk of cancer because of your family's situation.
2 :
The ACS (American Cancer Society) predicts that one in eight women will develop breast carcinoma at some point in their lives. You can ask your doctor to check your blood for the breast cancer associated genes. http://www.cancer.gov/cancertopics/factsheet/Risk/BRCA That will tell you if you are at a higher risk than the average woman in the U.S.
3 :
It is certain you will get cancer. Sorry.
4 :
you might have a higher risk but just get checked regularly. they mightve also all had the same habits that led them to get cancer, it might not all be genetic
5 :
i dont know its in the jeans
6 :
As a Natural Therapist that specialises in BioChemical Nutrition, I have have studied many forms of cancer, and only a very few of them are genetic in the cellular (DNA) sense. There is many research papers available on the web that show a strong link between diet and lifestyle and the incidents of cancer. An excess of animal products and their by products are strongly implicated in this reasearch as one of the leading causes. What I call the "non-cellular" genetics is when we learn our diet and lifestyle from our family tree. If your great grandad was a big meat eater and really liked his dairy and beer then your grandparent/s learned the same habits which they passed on to your parent/s, which are then passed on to you. Some of the baddies are: 1. Polyamines, which are endogenous Amino Acids that are intermediate products formed during the breakdown of dietary Amino Acids and dietary Proteins. (1) 2. Homocysteine is a toxic endogenous, sulphydryl-containing amino acid - a homologue of Cysteine. 3. Nitrosamines are a toxic group of Amines. They are organic oxides of Nitrogen that are formed within the body when Nitrites and Nitrates react with Amino Acids. 4a. Bar-b-qing may cause the production of various toxic substances in the foods (particularly Meats) that are barbequed that are potent initiators and promoters of many forms of Cancer. These carcinogens include Benzpyrene, Heterocyclic Aromatic Amines (HAAs) and Polynuclear Aromatic Hydrocarbons (PAHs). 4b. Food Irradiation may increase the risk of some forms of Cancer. 4c. Frying and overheating of dietary Oils causes the production of the (carcinogenic) Benzpyrene. 4d. Smoking (of foods) may cause the production of (carcinogenic) Benzpyrene. And many, many more. All of this info in available on the internet; just Google it. You can now, of course, choose to continue with these learned habits, or change them according to any new and enlightening information that you may receive. All the best with your research and decisions. : )
7 :
Hereditary cancer is rare; fewer than 10% of all cancer cases, all types, are hereditary. Cancer diagnosed after the age of 50 is even less likely to be hereditary. An isolated case of a type of cancer is not hereditary, nor is several family members having had different types of cancer. Only 50 10% of breast cancer cases are hereditary, and those are due to a rare inherited faulty gene. The fact that your father and his sister both had breast cancer suggests that it is possible that their cancers were due to on of the faulty genes known to be responsible for hereditary breast cancer, BRCA1 and BRCA2. This is the first thing you need to find out. If your father's breast cancer was due to him carrying one of the BRCA genes, then each of his children have a 50% chance of having inherited that gene. Any that have not inherited it are at no increased risk of breast cancer. Any that have inherited the gene are at increased risk of breast cancer, but that doesn't mean they will definitely develop it. For a female the risk is 50-80% over a lifetime of 70+ years, for a male the risk is 1% with the BRCA1 gene and 6% with the BRCA2 gene. I have a friend who carries one of the BRCA genes. Of her three adult children, one has inherited the gene and the other two haven't. If your dad's and aunt's cancers were due to one of te BRCA genes you may want to discuss genetic testing to see whether you too carry th gene with your doctor. It is also something to discuss with your doctor if you aren't able to establish that information. A sign that cancer MAY be hereditary within a family is when several members of the same side of that family have had the SAME type of cancer, especially if some have developed it at a younger than usual age. So the isolated incidences of leukaemia and liver cancer in your family don't increase your cancer risk.
8 :
It all depends on if you carry your father's gene. I got the Genetic testing done, because my father and all his side of the family had breast cancer. My test came out negative, and none on my mother's side has every had it, so the plain fact is, "I got it on my own." it is not necessarily true that you will follow the gene pool.

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Sunday, August 12, 2012

My dad and his sister had breast cancer, what is MY risk for the disease