Wednesday, July 8, 2009

What is the mode of inheritance of breast cancer


What is the mode of inheritance of breast cancer?
For my Biology class, we are doing a mini-symposium on genetic disorders. One of the topics i have to cover is mode of inheritance. Could anyone tell me what the mode of inheritance for breast cancer is?
Cancer - 1 Answers
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1 :
This site, http://www.ispub.com/journal/the_internet_journal_of_advanced_nursing_practice/volume_10_number_1_8/article/understanding_the_genetics_of_breast_cancer_a_clinical_overview.html Provides the information you're looking for. They explain the genetics of breast cancer far better than I could.
2 :
Hereditary breast cancer is rare; only 5 – 10% of all breast cancer cases are hereditary, and breast cancer diagnosed after the age of 50 is even less likely to be hereditary. There are two rare inherited faulty genes known to be responsible for hereditary breast cancer, Brca1 and Brca2. These genes can only be passed from parent (either one) to child. If someone inherits one of the faulty genes, each of his/her children has a 50% chance of inheriting that gene. Any child they have who inherits the gene has a 50% chance of passing it on to their own children. If any of their children don’t inherit the gene, nor will their own children Inheriting one of the genes does not mean one will definitely get breast cancer; that’s a 50 – 80% chance over a lifetime of around 75 years for a female, and for a male the risk is 1% with the BRCA1 gene and 6% with the BRCA2 gene over a lifetime


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